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The rate was highest in the first month of treatment

AOD 9604 doesn't affect IGF-1 levels, so there's no concern about unwanted tissue growth or increased cancer risk

We agree with commenters that this would result in several months not being included in the data calculations, effectively shortening the 12-month lookback period

Its interactions with the vagus nerve have been investigated in the context of brain-gut axis effects, including gastroparesis (delayed gastric emptying), where BPC-157 has shown consistent pro-motility effects in preclinical models through vagal cholinergic pathways

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