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The clinic-side priorities are pre-treatment screening for renal impairment, G6PD deficiency, congestive heart failure, and severe hypotension

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Additionally, it inhibits the elevation of serum copper levels and effectively mitigates the increase in CP activity following myocardial ischemia (126)

The two therapies do not share metabolic pathways or compete for the same receptors, so combining them does not create pharmacological conflicts