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The production of DHT was decreased by 33% in response to N while the values were similar to controls at NG 1 and increased further by 30% at NG 2, 3 and 4 (n = 6

It is important to refer that this mechanism of melanocytes apoptosis seems to occur in a low rate of Tregs/CD8 + T cells, i.e., insufficient Tregs suppressing melanocyte-specific CD8 + T cells, putting in anergy state or suppressing (Riding and Harris, 2019)

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Glutathione reduces melanin activity, protects against oxidative stress, improves skin hydration, and supports even tone