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Primary outcomes Compared to SGLT2i monotherapy, combination therapy with SGLT2i and GLP-1RA was associated with a lower risk of the primary composite outcome (HR, 0.87

We recommend building up to the standard dosage of 2 caps, 4 hours apart

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Given the high immunogenicity associated with the full-length CHIPS protein, CHOPS was designed as a minimized analogue that retains the essential receptor-binding residues identified from structural studies of CHIPS in complex with C5aR

Management: regular CBC monitoring, dose adjustment, hydration, blood donation if needed

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