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Combination Therapy Enters the Competitive Field CagriSema (Novo Nordisk), a once weekly injectable combination of semaglutide and the longacting amylin analogue cagrilintide, is expected to receive FDA approval by late 2026

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However, these findings strongly support that GLP-1RAs do not increase the risk of intestinal obstruction compared to non-GLP-1RA anti-diabetic medications

Patients may experience swelling, bruising, and discomfort

Retatrutide works through GIP, GLP-1, and glucagon receptors