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doi: 10.2174/1381612824666180712110447
These included: Expressive communication Personal and domestic daily living skills Interpersonal skills Play-leisure skills Coping social skills Other clinical improvements observed with B12 included improvements in: Sleep Gastrointestinal symptoms Hyperactivity Tantrums Nonverbal intellectual quotient Vision Eye contact Echolalia Stereotypy Anemia Nocturnal enuresis (bed wetting) Adverse events with B12 identified by meta-analysis included: Hyperactivity (11.9%) Irritability (3.4%) Trouble sleeping (7.6%) Aggression (1.8%) Worsening behaviors (7.7%) But adverse effects were generally few, mild, not serious, and not significantly different compared to placebo
Research surrounding Epithalon focuses on its potential influence on telomerase activity, circadian rhythms, and healthy aging pathways
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The Microbiome-Gut-Brain Axis in Health and Disease
These statements have not been evaluated by the FDA
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