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Approaches to restore the antitumor function of exhausted CD8 + T cells by remodeling mitochondrial metabolism, dynamics, and biogenesis have been shown to be effective, suggesting that mitochondria may be a potential target for future cancer therapies

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Zhang P, Chen L, Zhao Q, Du X, Bi M, Li Y, et al

426 Donepezil was approved for patients with mild and moderate AD in 1996 and was approved for patients with severe AD in 2006

322 reported that SSRIDDS is also associated with mutations in BICRA (BRD4 interacting chromatin remodeling complex-associated protein) gene