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Functional enrichment analysis further revealed that these genes were enriched in oxidative stressrelated pathways, including MAPK, Rap1, FoxO, and AMPK signaling pathways, which may contribute to the enhanced antioxidant capacity observed in PDHA1-overexpressing cells (Supplementary Fig

J Clin Onco 2022 ASCO Annual Meeting 40(supply 16), 2022

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For more long-term benefits like skin health and healthy aging support, it typically takes 30 to 60 days for cellular levels to stabilize and for visible or felt changes to become more apparent.

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