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Linagliptin added to sulphonylurea in uncontrolled type 2 diabetes patients with moderate-to-severe renal impairment
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When safety of the study participants and technological developments allow, so called biomarkers can be used to collect PD data to understand if the drug reaches the target, binds to the target and exerts its expected pharmacological activity within the dose range tested
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Gardner PR, Nguyen DD, White CW
These patents prevent generic competition until expiration dates arrivesometimes a decade away
doi:10.3389/fmicb.2024.1435720 40
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