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Semaglutide belongs to a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which mimic the action of the naturally occurring hormone GLP-1 produced in the intestines

Retatrutide, a triple-agonist (GLP-1, GIP and glucagon), is in late-stage trials and has produced even more weight loss in early data up to 24% at 48 weeks in phase 2

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Bariatric surgery involves physical changes to your stomach and intestines that decrease the amount of food you eat and reduce how much your body can absorb

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Kastner M