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Most visible differences stem from the natural process of fat reduction

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The UK Prospective Diabetes Study (UKPDS) suggested that the rate of beta cell deterioration associated with metformin was similar to that associated with diet alone or sulfonylureas [19]

2020;9(Suppl 1):S55S65

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doi: 10.3389/falgy.2025.1618466 Received 26 April 2025 Accepted 28 May 2025 Published 16 June 2025 Volume 6 - 2025 Edited by Akira Yamasaki, Tottori University, Japan Reviewed by Tomoya Harada, Tottori University Hospital, Japan Jos J