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( D ) Kinetics of GSH-mediated cyt c reduction in the presence of either GSSSG or GSSSSG

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doi: 10.1016/j.chembiol.2019.02.003 106 TawarayamaHUmekiKInoue-YanagimachiMTakahashiNHasegawaHHimoriNet al

Cellular effects duration vs plasma half-life Critical distinction: Plasma half-life duration of effects GHK-Cu clears blood in hours But cellular effects last days How GHK-Cu works: Peptide binds to cell surface receptors Triggers intracellular signaling cascades Activates gene expression changes Initiates collagen synthesis, wound healing, etc

[82] Codd, E.E

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