111 The only acceptable alternative endpoint in drug development, histological evidence, consists of the resolution of steatohepatitis and no worsening of liver fibrosis, or improvement in liver fibrosis of at least one stage without worsening of steatohepatitis
Then increase to 0.75mL placed under the tongue daily as the final dosage level
Also, watch for symptoms that worsen after 48 hours or if a fever above 100.4F develops
Weight regain of 10-20% is common at 5+ years, but the anatomical change is permanent
However, they noted these benefits were a somewhat modest 10 to 20 percent reduction in most risks
The short answer is yes, alcohol in moderation on a weight loss drug may be okay if your doctor says so (keep in mind that drinking carries health risks of its own)