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Collectively the results from these studies will be valuable in better assessing the benefits of metformin on healthspan and also fine-tuning future larger studies such as TAME

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Data Availability Sharing is not applicable to this article as no datasets were generated or analyzed during the current study

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In contrast, greater MP was reached on all bouts with the 1.5 g/d dosage with gains across the five sprints of +4.9%, +1.7%, +2.7%, +2.9%, and +5.1% compared with baseline