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(2015) have recently reported that paclitaxel treatment may also trigger pro-inflammatory mechanisms in DRG neurons via toll-like receptor 4, which is also associated to the sensitization of TRPV1

In addition, there was an enhancement in the messenger RNA (mRNA) expression of cyclooxygenase 2 (COX-2)

Liu, T., Jiang, L., Tavana, O

Marissa Liza: Yes, there's been a lot of research done, again, only on animals and, but I also wonder why haven't they tested it further on humans, right

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Evidence gaps Long-term (5+ year) outcomes data is still being collected