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PMID 17619527

Oral semaglutide should NOT be taken while breastfeeding

Compared with untreated individuals, those receiving GLP-1 therapy showed lower levels of pro-inflammatory cytokines (IL-6, TNF-, IL-12), higher levels of IL-10, reduced expression of endothelial adhesion molecules (ICAM-1, VCAM-1), and decreased leukocyte rolling and adhesion along the vascular endothelium [15]

However, although trials have shown the drugs to be safe and effective, they are not without their side-effects most commonly nausea, vomiting, diarrhoea, constipation and decreased appetite

These medications differ in their mechanisms, administration routes, and clinical applications

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