For payers, the expectation should be that international reference pricing will eventually become embedded in the American system
Frequently Asked Questions Research Use Only: This product is for laboratory research purposes only
Lilly removed this from the slide deck, but I managed to snag a picture at the presentation We can see the women in the trial were already at 30.8% weight loss at 80 weeks on the max dose with the 9mg dose only 2% behind and both still losing weight
Clinical trials are ongoing, and it is only available through medically supervised settings
Researchers optimizing their protocols should track: Body composition: Use DEXA scans, bioimpedance devices, or at minimum waist/hip measurements to distinguish fat loss from lean mass loss Resting heart rate: Particularly important with retatrutide due to the glucagon-mediated heart rate increase Blood pressure: Both peptides lower blood pressure, which is beneficial but can cause dizziness if the drop is too rapid Fasting blood glucose: Especially relevant for those managing pre-diabetes or type 2 diabetes Liver enzymes: For anyone with suspected or confirmed fatty liver disease Energy levels and sleep quality: Subjective but important indicators of protocol tolerance The GLP-1 progress tracking tools available through SeekPeptides help members monitor these metrics systematically rather than relying on memory or sporadic tracking
Coskun T, Sloop KW, Loghin C, Alsina-Fernandez J, Urva S, Bokvist KB, Cui X, Briere DA, Cabrera O, Roell WC, et al
