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1997;112:A400

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The in vivo model utilized 10-week-old male C57BL/6 mice that were housed in environmentally controlled conditions with a 12-hour dark-light cycle, receiving standard laboratory chow and water ad libitum

The mechanisms of action for butyrate are due to the fact that it helps regulate gene expression, supports intestinal homeostasis and energy metabolism, and is an anti-inflammatory (Liu et al., 2018)