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10.1016/j.cell.2025.03.005 258 LeeH.-J.LeeK.-E.KimJ.-K.KimD.-H

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Amy Arnstens group showed that it acts on the dendritic spines of prefrontal neurons by closing HCN ion channels, raising the gain of the networks that hold information in mind while the drug is present

The replication details were performed as follows: two days of foot food and one day of fasting, ammonia (0.1%) and sodium deoxycholate solution (20 mmol/L) as drinking water were used alternately every day