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Furthermore, upregulation of multiple genes controlled by Nrf2 indicates Nrf2 activation, possibly due to the increase of SQSTM1/p62 by autophagy deficiency

2.9 Histological and immunofluorescence examination The animals were sacrificed, and the organs were isolated and transferred to Eppendorf tubes prefilled with 4% paraformaldehyde

Cancer 9 , 701713 (2009)

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