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Products marketed online as injections, nasal sprays, or other preparations are not equivalent to an FDA-approved drug

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For equivalent lipotropic activity, oral dosing would require 23 the methionine content of an injection and even then, peak plasma concentration is lower and shorter-lived

Individuals with reduced activity of the DHFR enzyme, which is responsible for the first step in folic acid metabolism, may be less able to convert folic acid efficiently