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45 weeks of age) were housed in climate-controlled rooms (23 1C) with a 12:12 h lightdark cycle

Possible reasons include Type 1 diabetes diagnosis, advanced Type 2 diabetes with severely depleted beta cells, contraindication to GLP-1 drugs (thyroid cancer history, pancreatitis history), insurance or cost barriers, prior GLP-1 intolerance, or very high blood sugar requiring immediate insulin coverage

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Research suggests it might be more effective than medications that target only GLP-1

Neural effects of gut- and brain-derived glucagon-like peptide-1 and its receptor agonist

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