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Ensure adequate fluid intake and contact your GP if symptoms are severe or prolonged Changes in mood or mental health : Whilst sertraline treats depression and anxiety, any worsening of mental health symptoms, emergence of suicidal thoughts, or unusual behavioural changes should be reported immediately Appetite changes : Significant loss of appetite or difficulty eating adequate nutrition requires medical review Signs of pancreatitis : Severe abdominal pain radiating to the back, nausea, and vomiting warrant urgent medical assessment, as GLP-1 agonists carry a small risk of pancreatitis [1] [5] Gallbladder problems : Wegovy and rapid weight loss can increase the risk of gallstones and gallbladder inflammation
Swelling in legs, ankles, or feet (peripheral edema) combined with weight gain can indicate heart failure, kidney dysfunction, or venous insufficiency
For example, high-fat meals or overly sugary foods might irritate your stomach, making it harder to stick with your treatment
Your GP can assess whether your symptoms are related to iron deficiency, your diabetes medication, or another underlying cause
At sacrifice, heart tissue was immediately harvested, and the heart was perfused and fixed with 10% neutral-buffered formalin (NBF) for 24 h
