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5.3.5 Inhibition of cell invasion and migration Artesunate inhibits the proliferation, migration, and invasion of A549 and H1299 cells and induces their apoptosis, possibly due to reduced HuR and MMP-9 protein expressions (Hu et al., 2022)

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E-64c and E-64d were each purchased from Selleck Chemicals (S7392 and S7393) and dissolved to 1.25 mg ml 1 (3.7 mM) in 66% methanol

Specifically, bloodletting puncture can suppress the expression of MAPK, ERK, p38, and their downstream molecules, MMP9 and AQP4, leading to enhanced neurological function, reduced brain edema, stabilization of the bloodbrain barrier, and decreased apoptosis

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Food and Drug Administration) Long-term data are limited