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References Torres-Mora J, Dry S, Li X

NICE guidance (NG28) recommends individualised monitoring plans, structured patient education, and 36 monthly HbA1c reviews to optimise GLP-1 therapy and ensure safe diabetes management

MOTS-c is a mitochondrial signalling peptide that senses cellular stress and activates AMPK-centred pathways to maintain homeostasis

Plan regular, structured meals rather than grazing throughout the day

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Adverse Reactions (6.1).] Add-on Combination Therapy with Insulin (with or without Metformin) A total of 641 patients with type 2 diabetes participated in a 24-week, randomized, double-blind, placebo-controlled study designed to assess the efficacy of JANUVIA as add-on to insulin therapy (with or without metformin)