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It slows down how fast your stomach empties, so you stay full longer

An essential role of Nogo-B in regulating vascular remodeling was reported in Nogo-A/B-deficient mice [219]

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10.1038/nrn1248 Summary Keywords inhibitory neurons, neocortex, hippocampus, synaptic plasticity, homeostasis, homosynaptic plasticity, heterosynaptic plasticity Citation Bannon NM, Chistiakova M and Volgushev M (2020) Synaptic Plasticity in Cortical Inhibitory Neurons: What Mechanisms May Help to Balance Synaptic Weight Changes

it can penetrate certain CNS regions, which are essential for appetite control and hunger and are not protected by the blood-brain barrier

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