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Molecular modeling suggested that AEDG may bind to histone H1 regions that interact with DNA, providing a proposed epigenetic mechanism for changes in neurogenesis-related gene expression and protein synthesis

Available evidence suggests a role for voltage-dependent anion channel (VDAC), located in the OMM, and adenine nucleotide translocase (ANT) across the IMM ( 2 + -induced swelling and MPT, although at a higher threshold, which has been interpreted as evidence against a role for ANT in MPT (Sileikyte et al., 2014)

Additionally, Syn constructs containing a C-terminal cysteineSyn 1103 -104C and Syn S129E -141Cwere generated by site-directed mutagenesis for MST-based binding studies, as previously described 35

The central nervous system (CNS) depends almost exclusively on glucose to obtain energy, and the retina is part of the CNS

JNCI: J Natl Cancer Institute