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Tomaro-Duchesneau C, LeValley SL, Roeth D, et al

Abrupt jumps skip the tolerability buffer and are the most common cause of severe nausea

You should not take a GLP-1 drug if you have severe gastrointestinal conditions like inflammatory bowel disease (IBD) or gastroparesis or a personal or family history of multiple endocrine neoplasia 2A, multiple endocrine neoplasia 2B, medullary thyroid cancer, or pancreatitis

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The consultation itself is conducted by a licensed physician, but patients have no way to verify who that physician is before the visit

These alternatives typically show lower efficacy than GLP-1s but provide meaningful benefits at reduced cost