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The potential mechanisms were found to be related to regulating neurotransmitter (5-Hydroxytryptamine) and inflammatory factor levels, and importantly, blocking the JAK2/STAT3 signaling pathway effectively alleviated depressive symptoms in BC combined with depression mice, inhibiting tumor progression (Kumar and Roy, 2023)

3.64 mg/l in controls) (Table 2)

Building on these classic observations, more mechanistic studies have proposed functional explanations for the relationship between the Bacteroidetes to Firmicutes ratio and host energy balance

Hiebl, J