Wilkins et al., 2012), mainly in kidney and liver, and tricarboxylate carrier (TTC, SLC25A1) in brain mitochondria and astrocytes (Wadey et al., 2009)
All animal experiments were conducted under strict governmental and international guidelines and were approved by the local government for the administrative region of Upper Bavaria, Germany
Low levels of GSH or LC may lead to elevated levels of ROS and oxidative stress, impaired reduction of oxidized GSSG to GSH, and/or heightened consumption of GSH compared to its production [63,86,89,95,96]
8 (download XLSX Source data Extended Data Fig
A subgroup of individuals with autism may show evidence of mitochondrial stress or altered energy metabolism
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