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Some of the important identified risk factors for ASD include advanced parental age, in utero exposure to drugs, toxins, alcohol, and tobacco smoke, as well as maternal disease and infection during pregnancy (161)

Trabalhos recentes sugerem uma interao com a via JAK-2/STAT-3, envolvida na resposta inflamatria e na sobrevivncia celular, reforando a hiptese de um mecanismo de ao pleiotrpico

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