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After 12 weeks of feeding, mice in the HFD group were subdivided into high-fat diet control group (HFD, n=9) and semaglutide intervention group (HFD+sema, n=9)

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32, 33 This hypothesis is supported by observations that the first-degree relatives of Crohns disease (CD) patients are at increased risk of developing IBD and some of these relatives also demonstrate mucosal leakiness

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