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For the assessment of the changes from baseline following GLP-1-based therapies in % FMD and IMT, mean differences with 95% confidence intervals (CI) were calculated between baseline samples and end-of-treatment samples for each study and then an overall effect size was generated

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In summary, selection bias and residual confounding potentially contributed to the results of this study which question the validity of the study results

Endo, Y., Furuta, A

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En contraste, los que recibieron placebo tuvieron un incremento de tres veces en la permeabilidad intestinal