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Cultures were incubated at a constant temperature of 37 C in an atmosphere comprising 94% N 2 , 5% CO 2 , and 1% O 2

It is usually induced in animal models by immunization with antigens from the thyroid, such as thyroglobulin or thyroid peroxidase, which induce the production of autoantibodies that attack thyroid cells (Liu et al

European Journal of Clinical Nutrition, [online] 72(1), pp.105111.

Adsorptive-mediated transport at the BBB has also been exploited to target nanocarrier systems by using cationic lipids and cell penetrating peptides to increase binding and internalization at the brain capillary endothelium [29, 30], which has a highly negative surface charge [31]

Mild edema or water retention: Occasional, dose-related

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