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Many other GLP-1 RAs are currently under clinical investigation, exploring additional therapeutic areas such as liver disease, kidney disease, and even neurodegenerative disorders

Experts say, however, that Ozempic penis is not a true side effect of GLP-1 drugs

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But so is the cost: each generation adds more gastrointestinal side effects, and retatrutide introduced a new signal (dysesthesia) that did not appear in Phase 2

The landmark SURMOUNT-1 trial demonstrated that participants receiving the highest dose of tirzepatide lost up to 22.5% of their total body weight over 72 weeks

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