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Factors influencing variation in basal metabolic rate include fat-free mass, fat mass, age, and circulating thyroxine but not sex, circulating leptin, or triiodothyronine

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Human pharmacokinetic data confirms sustained plasma glutathione levels supporting extended cellular antioxidant protection

Metastatic RCC patients receiving ICI therapy who developed irAEs had a median OS of 35.9 versus 26.5 months