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For runners, thats a dangerous trade-off. The appetite suppression inherent in the medications can also make it difficult to meet your caloric needs, especially during high training loads

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The abdomen was soft, and genital examination showed normal male genitalia

Clinical trial data for adolescents are generally limited to 1-2 years, so long-term effects require ongoing evaluation

Table 2 Results summary of metabolite changes in recent clinical studies investigating associations between gut-derived metabolites and the MedDiet

Tham et al, 2015])