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The seven-day half-life answers all these questions

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A phase 2 clinical trial published in The New England Journal of Medicine enrolled 338 patients with a body-mass index of 30 or higher or those with a BMI of 27 to less than 30 with at least one weight-related condition

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If approved, it would likely follow similar criteria as current weight-loss medications: BMI 30 BMI 27 with metabolic conditions Possibly type 2 diabetes Final eligibility would depend on FDA guidelines

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Back Lund PK, Goodman RH, Dee PC, Habener JF (1982) 'Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem', Proceedings of the National Academy of Sciences , 79, 345-49

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