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This suggested the presence and potency of intestine-secreted insulinotropic hormones (incretins)

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Example 7 preparation of a Semetreuptade backbone peptide resin 17.8 g (5mmol) of Fmoc-Gly-1- (2-hydroxyethyl) imidazole hexafluorophosphate-Merrifield Resin (Sub 0.28mmol/g) obtained in example 3 was weighed into the reaction column, washed 3 times with DCM and swollen with DMF for 30 min