Animal studies have suggested that GLP-1s act on the mesolimbic reward pathways and reduce drug reinforcement in alcohol, nicotine, cocaine, and opioid use disorders
The interaction is not a direct pharmacokinetic clash but rather a compounded physiological effect
2021;13(10):mfab055
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Eur J Hum Genet 24(12):17921796 Ortiz-Genga MF, Cuenca S, Dal Ferro M, Zorio E, Salgado-Aranda R, Climent V, Padrn-Barthe L, Duro-Aguado I, Jimnez-Jimez J, Hidalgo-Olivares VM, Garca-Campo E, Lanzillo C, Surez-Mier MP, Yonath H, Marcos-Alonso S, Ochoa JP, Santom JL, Garca-Giustiniani D, Rodrguez-Garrido JL, Domnguez F, Merlo M, Palomino J, Pea ML, Trujillo JP, Martn-Vila A, Stolfo D, Molina P, Lara-Pezzi E, Calvo-Iglesias FE, Nof E, Cal L, Barriales-Villa R, Gimeno-Blanes JR, Arad M, Garca-Pava P, Monserrat L (2016) Truncating FLNC mutations are associated with high-risk dilated and arrhythmogenic cardiomyopathies
Q: What should people know before using GLP-1s