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That has been true for retatrutide as well, according to recent study results

Use of insulin or sulfonylureas (hypoglycemia risk)

263 Multiple clinical studies over the last few years have found that several GLP-1R agonists have beneficial effects on diabetic kidney disease independent of their glucose-lowering actions mediated by natriuresis, anti-inflammatory and anti-oxidative stress properties, and suppression of renal fibrosis

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Paladugu L, Gharaibeh A, Kolli N, Learman C, Hall TC, Li L, et al

However, as this was an observational target trial emulation conducted in a predominantly male Veterans Affairs population, the results support but do not establish causality and may have limited generalisability to broader populations, particularly women and non-veteran groups