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Nausea, constipation, and reduced appetite are the most frequently reported side effects, typically mild to moderate and manageable with gradual dose escalation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Delmeire D., Flamez D., Hinke S.A., Cali J.J., Pipeleers D., Schuit F

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Patients with severe symptoms particularly those with weakness, atrophy, or constant numbness are surgical candidates from the start, because nerve damage that's allowed to progress may not recover even after surgery