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Description

injections of doses of 20, 100, or 500 g/kg to rats, the peak time (Tmax) of each dose was 3 min, while the Cmax of each dose was equivalent to 12.3, 48.9, and 141 ng/mL, respectively

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PPM:100,000

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IV push, IV infusion over a set time, IM injection into a muscle, etc.)

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Healing bone requires balance between protection (preventing re-injury) and loading (stimulating proper remodeling)

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It is not yet FDA-approved

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As our previous study confirmed that Clopidogrel activates the p38/MAPK signaling pathway followed by up-regulation of C/EBP homologous transcription factor ( CHOP ), and culminating with ER stress apoptosis in human gastric mucosal epithelial cell line GES-1

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