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Source: The New England Journal of Medicine Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff et al., 2022) Figure 1A Average Weight Loss After 72 Weeks At 72 weeks, participants taking tirzepatide once weekly lost significantly more weight than those on placebo: 5 mg dose: 15.0% average body weight reduction 10 mg dose: 19.5% reduction 15 mg dose: 20.9% reduction Placebo: 3.1% reduction All tirzepatide doses showed much greater weight loss compared to placebo

A Cleveland Clinic team led by cardiologist Amgad Mentias, MD, recently published a large database analysis showing that bariatric surgery in Medicare enrollees with obesity was associated with lower risk of mortality, new-onset heart failure and myocardial infarction ( J Am Coll Cardiol

Wilbon, M.G

It is also generally considered non-comedogenic, meaning it is unlikely to clog pores, which is a key concern for subjects with acne-prone skin

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Influence on Brain Signals Related to Hunger Ozempic affects the brains regulation of appetite and satiety