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It is currently under clinical investigation and has not yet received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

Compelling findings from germ-free (GF) animal studies have demonstrated that the absence of microbiota leads to substantial neurodevelopmental abnormalities and altered behavior (Sudo et al., 2004

Cells were harvested at 12,000 x g for 15 min at 18 C and stored at 20 C until purification

The dotted line represents P = 0.05

"The success of regulated GLP-1 drugs has 'normalised' using a needle, lowering the psychological barrier to self-injection

Tirzepatide is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)