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Enzyme function is also compromised by copper deficiency, including that of copper-zinc SOD (Cu-Zn SOD), resulting in a weakened antioxidant defence system and increased vulnerability to oxidative stress, contributing to the development of atherosclerosis (103)

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Patients with conditions showing strong preclinical evidence and limited alternative treatment options may represent reasonable candidates following thorough informed consent discussions

AGE-RAGE signal generates a specific NF-B RelA barcode that directs collagen I expression