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However, GGC consists of a gamma-glutamyl bond which makes it resistant to hydrolysis by endoproteases (Anderson and Meister, 40 -induced inflammation may, thus, be also due to chelation of redox-active metals and additional antioxidant mechanisms (Figure 6)

Because disorders of the GI tract can interfere with the absorption of B12, the level of this vitamin in the blood is sometimes used as a test of gut health

Having ups and downs is part of the process, says Dr

In the same manner as ROS cause PR damage, iron overload can cause lipid peroxidation and oxidative stress, leading to ferroptosis and subsequent PR damage (166)

Great efforts have been devoted to the identification of genetic, humoral and cellular biomarkers predictive of irAEs associated with ICIs

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