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Injectable GLP-1 treatments, like Mounjaro and Wegovy, have a peptide-like structure

GLP-1 agonists also stimulate pancreatic beta cells to secrete insulin and tamp down glucagon secretion from the pancreatic alpha cells

SURMOUNT-1 subgroup data from 2,542 women showed tirzepatide produced ~23% body weight reduction in peri/postmenopausal women vs 3% on placebo

Which Interventions Reduce Side Effects in Practice The evidence points consistently in one direction: most GI side effects are manageable, and how they are managed determines whether patients stay on treatment long enough to benefit

Both produce satiety, but in different brain regions

P =0.048), prostate (IRR, 2.70