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Most studied potential mechanisms include neuroplasticity effect, oxidative stress and neurotransmitter regulation

In addition to blunted monoaminergic neurotransmission, it was also shown that deficiency in neurotrophic factor effects, disturbances in neurogenesis and synaptogenesis, chronic neuroinflammatory processes, and dysregulation of the hypothalamicpituitaryadrenal (HPA) axis can largely contribute to the manifestation of depressive symptoms in patients [3,4,5]

FeelGood reports that patients on its GLP-1 program lose 15-20% of body weight on average

The individual actions of GLP-1R and GIPR activation are difficult to separate out

We permanently lose the capability to make enough glutathione to deal with normal levels of free radicals in some of our cells, tissues and organs

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