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However, this method should only be done under medical supervision and is typically recommended in clinical settings rather than for routine self-use

Furthermore, the expression of MMP2 and MMP9 downregulated while the expression of TIMP1 increased

1 H NMR (500 MHz, DMSO) 7.95 (t, J = 38.4 Hz, 5H), 7.41 (p, J = 5.1, 3.9 Hz, 18H), 7.23 (d, J = 7.4 Hz, 2H), 7.09 (d, J = 7.4 Hz, 12H), 6.96 (d, J = 19.0 Hz, 2H), 6.70 (q, J = 9.2, 8.1 Hz, 4H), 4.56 (d, J = 54.2 Hz, 2H), 4.18 (d, J = 69.9 Hz, 3H), 3.56 (tt, J = 18.3, 9.3 Hz, 7H), 3.03 2.77 (m, 10H), 1.66 1.20 (m, 54H)

10.1016/j.bioorg.2017.10.006 90 Sharifi-RigiA.HeidarianE.AminiS

The blood-brain barrier: an overview: structure, regulation, and clinical implications